The access of photovoltaics changes the structure and power flow of distribution network, thus collapsing traditional pattern by single-phase power supply. The change of system flow inevitably affects the voltage quality, economic indicators and safety of distribution network. Considering the impacts that photovoltaic access to distribution network brings, a multi-objective optimization method based on interactive decision mathematical model is proposed. Firstly, it takes into account the comprehensive factors including different access capacities, dense and decentralized access of photovoltaic which affect the voltage and line loss. Then, the optimal model of photovoltaic access is established. Finally, from the impact of access to photovoltaic on the key indicators of distribution network, the most optimal solution for photovoltaic access is found. By the analysis of De 31 Dedubei, the proposed multi-objective optimization method provides a theoretical basis for the planning and design of photovoltaic power generation projects.