Peak-valley time-of-use tariff is an effective price-based demand response strategy.Through reasonable time-of-use tariff, energy demanders can provide sufficient and efficient price signals, so as to achieve the goal of peak-filling of energy demand.The integrated energy system combines electricity, heat, cold, gas and other energy forms, and can achieve economic dispatch among different energy forms through a certain dispatching strategy.In this context, firstly, the energy hub modeling technology is used to achieve the effective modeling of the participating units in the integrated energy system.Secondly, the traditional research on demand response for electric load is extended to the research on demand response for cold and hot load, and a comprehensive energy demand response model including demand response for electric, thermal and cold load is established.The model is solved by using YALMIP/CPLEX optimization solver based on Matlab platform.Finally, the simulation results of different scenarios show that considering the comprehensive energy demand response in the context of time-sharing tariff is not only conducive to load peak-shaving and valley filling, but also has a certain role in improving the dispatching economy of the system.