Under the premise that current smart meters are widely used, real-time monitoring of end-user voltage deviations, and based on station-line-transformation-household vertical aggregation, construct a comprehensive supply voltage qualification rate for distribution transformers, a comprehensive supply voltage qualification rate for feeders, and a comprehensive supply voltage qualification rate for substations. Other indicators are used to measure the voltage quality of local areas of the distribution network. According to this indicator, the time characteristics of low voltage in the area are analyzed, and the optimized reactive power compensation is used to improve the voltage quality. With the regional comprehensive power supply voltage qualification rate, distribution network reliability index, and grid loss as the objective functions, set power flow constraints and line constraints. Based on the constraint conditions, a regional reactive power compensation strategy for the distribution network based on the comprehensive supply voltage qualification rate is established, and the genetic algorithm is used to solve it. The matlab platform and IEEE-33 nodes are used for simulation research to verify its feasibility.