For integrated energy systems that couple multiple forms of energy such as electricity, gas, coldand heat. Integrated demand response(IDR) of demand-side resources such as flexible loads, energy storage, and electric vehicles is conducive to tapping the response potential of multi-energy loads, stimulating integrated energy flexibility of the system and improving energy efficiency. Firstly, based on the regional electric-gas integrated energy system, a park-level cold-heat-electric-gas integrated energy system is constructed. Then, an integrated energy system scheduling model is established. The node energy balance equation is used to analyze the node energy price and clarify the dispatch-energy price-integrated demand response transfer relationship of the system. Based on the nodal energy price, the IDR model considering flexible loads, energy storage and electric vehicles as participants is established. Finally, the flexible load, energy storage, and electric power are analyzed through examples. The response of the electric vehicle is analyzed based on the energy prices of the nodes, and the load curves before and after IDR of the multi-energy users in different locations are analyzed. Ther analysis shows that while improving user utility, making full use of flexible load characteristics can effectively reduce operating costs.